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Giovanna Lattanzi Selected Research

Laminopathies

1/2024Desmin and Plectin Recruitment to the Nucleus and Nuclei Orientation Are Lost in Emery-Dreifuss Muscular Dystrophy Myoblasts Subjected to Mechanical Stimulation.
1/2023Impact of Combined Baricitinib and FTI Treatment on Adipogenesis in Hutchinson-Gilford Progeria Syndrome and Other Lipodystrophic Laminopathies.
2/2022The wide and growing range of lamin B-related diseases: from laminopathies to cancer.
1/2022The role of prelamin A post-translational maturation in stress response and 53BP1 recruitment.
1/2020Cytokine Profile in Striated Muscle Laminopathies: New Promising Biomarkers for Disease Prediction.
1/2020Lamin A involvement in ageing processes.
2/2019The Cutting Edge: The Role of mTOR Signaling in Laminopathies.
1/2019Ankrd2 in Mechanotransduction and Oxidative Stress Response in Skeletal Muscle: New Cues for the Pathogenesis of Muscular Laminopathies.
1/2019Statins and Histone Deacetylase Inhibitors Affect Lamin A/C - Histone Deacetylase 2 Interaction in Human Cells.
4/2018Lamins and bone disorders: current understanding and perspectives.
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Giovanna Lattanzi Research Topics

Disease

30Laminopathies
01/2024 - 01/2005
13Emery-Dreifuss Muscular Dystrophy (Scapuloperoneal Muscular Dystrophy)
01/2024 - 04/2003
13Progeria (Hutchinson Gilford Syndrome)
01/2023 - 09/2009
9Lipodystrophy
11/2023 - 06/2005
8Familial Partial Lipodystrophy (Dunnigan Syndrome)
11/2023 - 11/2003
6Neoplasms (Cancer)
02/2022 - 05/2015
5Inborn Genetic Diseases (Disease, Hereditary)
10/2023 - 01/2005
5Osteosarcoma (Osteogenic Sarcoma)
01/2021 - 03/2002
4Genomic Instability
12/2021 - 11/2019
4Cardiomyopathies (Cardiomyopathy)
04/2021 - 06/2012
3Ewing Sarcoma (Sarcoma, Ewing)
01/2022 - 07/2004
3Limb-Girdle Muscular Dystrophies (Limb-Girdle Muscular Dystrophy)
01/2020 - 12/2003
3Muscular Dystrophies (Muscular Dystrophy)
10/2018 - 04/2011
3Werner Syndrome (Werner's Syndrome)
07/2010 - 06/2005
2Autosomal Emery-Dreifuss Muscular Dystrophy
01/2019 - 01/2017
2Disease Progression
01/2019 - 06/2013
2Bone Resorption
10/2015 - 09/2008
2Rare Diseases (Rare Disease)
07/2011 - 09/2009
1Cockayne Syndrome (Syndrome, Cockayne)
10/2023
1UV-Sensitive Syndrome
10/2023
1Cardiac Sudden Death (Sudden Cardiac Arrest)
03/2022
1Brain Diseases (Brain Disorder)
02/2022
1Hypertrophy
01/2022
1Carcinogenesis
01/2021
1Kyphosis
01/2021
1Inflammation (Inflammations)
01/2020
1Atrial Fibrillation
11/2019
1Melanoma (Melanoma, Malignant)
01/2018
1Heart Failure
01/2018
1Heart Diseases (Heart Disease)
01/2018
1Ventricular Tachycardia
01/2018
1Bradycardia
01/2018
1Stroke (Strokes)
01/2018
1Atherosclerosis
10/2015
1Sarcoma (Soft Tissue Sarcoma)
05/2015
1Rhabdomyosarcoma
05/2015
1DNA Repair-Deficiency Disorders (Chromosome Instability Syndromes)
06/2013
1Osteolysis
09/2008
1Osteoporosis
09/2008
1Infections
03/2008
1Cytomegalovirus Infections (Inclusion Disease)
03/2008

Drug/Important Bio-Agent (IBA)

30Lamin Type A (Lamin A)IBA
01/2024 - 04/2003
17prelamin AIBA
01/2022 - 06/2005
12Proteins (Proteins, Gene)FDA Link
10/2023 - 12/2003
11LaminsIBA
02/2022 - 11/2003
5HeterochromatinIBA
01/2020 - 01/2007
4emerinIBA
01/2020 - 04/2003
4ChromatinIBA
03/2016 - 10/2005
3Lamin Type B (Lamin B)IBA
02/2022 - 03/2008
2MicroRNAs (MicroRNA)IBA
01/2022 - 01/2020
2DNA (Deoxyribonucleic Acid)IBA
12/2021 - 10/2011
2DNA Transposable Elements (Element, IS)IBA
01/2020 - 01/2020
2Biomarkers (Surrogate Marker)IBA
01/2020 - 01/2018
2Transforming Growth Factor beta (TGF-beta)IBA
01/2020 - 04/2018
2MTOR InhibitorsIBA
01/2019 - 11/2016
2Carrier Proteins (Binding Protein)IBA
01/2019 - 04/2011
2Sirolimus (Rapamycin)FDA Link
11/2016 - 10/2015
2PPAR gammaIBA
06/2005 - 03/2002
1DesminIBA
01/2024
1PlectinIBA
01/2024
1Mineralocorticoid Receptors (Mineralocorticoid Receptor)IBA
11/2023
1baricitinibIBA
01/2023
1monoaminocarboxydihydroboraneIBA
01/2023
1desmuslin (synemin)IBA
04/2021
1tocilizumab (atlizumab)FDA Link
01/2021
1Interleukin-17 (Interleukin 17)IBA
01/2020
1TESIBA
01/2020
1Interleukin-4 (Interleukin 4)IBA
01/2020
1Granulocyte Colony-Stimulating Factor (G-CSF)IBA
01/2020
1CytokinesIBA
01/2020
1Interleukin-8 (Interleukin 8)IBA
01/2020
1ChemokinesIBA
01/2020
1Karyopherins (Importin)IBA
01/2020
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2020
1AF 57IBA
11/2019
1Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA
02/2019
1Protein Isoforms (Isoforms)IBA
01/2019
1Large-Conductance Calcium-Activated Potassium Channels (Maxi-K Channels)IBA
11/2018
1DecitabineFDA Link
01/2018
1AntigensIBA
01/2018
1RNA (Ribonucleic Acid)IBA
01/2018
1Therapeutic UsesIBA
11/2016
1Small Interfering RNA (siRNA)IBA
03/2016
1Histones (Histone)IBA
10/2015
1Tretinoin (Retinoic Acid)FDA LinkGeneric
10/2015
1MC1742IBA
05/2015
1TubulinIBA
05/2015
1MC2625IBA
05/2015
1Histone Deacetylase InhibitorsIBA
05/2015
11,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA
10/2011
1Cysteine (L-Cysteine)FDA Link
10/2011
1lamina-associated polypeptide 2IBA
04/2011
1Nuclear Matrix-Associated ProteinsIBA
04/2011
1Peptides (Polypeptides)IBA
04/2011
1Protein PrecursorsIBA
07/2010
1Nuclear Localization Signals (Nuclear Localization Signal)IBA
07/2008
1Viral ProteinsIBA
03/2008

Therapy/Procedure

3Heart Transplantation (Grafting, Heart)
03/2022 - 10/2013
3Therapeutics
01/2019 - 02/2008
1Cardiac Resynchronization Therapy
01/2018